Parallel evolution of circulating FABP4 and NT-proBNP in heart failure patients
نویسندگان
چکیده
منابع مشابه
Parallel evolution of circulating FABP4 and NT-proBNP in heart failure patients
BACKGROUND Circulating adipocyte fatty acid-binding protein (FABP4) levels are considered to be a link between obesity, insulin resistance, diabetes, and cardiovascular (CV) diseases. In vitro, FABP4 has exhibited cardiodepressant activity by suppressing cardiomyocyte contraction. We have explored the relationship between FABP4 and the N-terminal fragment of pro-B-type natriuretic peptide (NT-p...
متن کاملAnalysis of circulating forms of proBNP and NT-proBNP in patients with severe heart failure.
BACKGROUND The specific forms of pro-B-type natriuretic peptide (proBNP) that occur in human blood are not yet clear. We demonstrated the presence of several proBNP forms in human plasma with a new affinity chromatography method that can be used in combination with nano-liquid chromatography electrospray ionization tandem mass spectrometry (nano-LC-ESI-MS/MS). METHODS For affinity chromatogra...
متن کامل[Stability of NT-ProBNP in patients with systolic heart failure].
Natriuretic peptides are extremely useful in the diagnosis and prognosis of patients with heart failure. However, it is not clear whether their values are stable. We carried out a prospective study of 30 consecutive ambulatory patients (mean age, 62.6 [12.2] years) with stable systolic heart failure, as determined by the 6-minute walk test, who were in New York Heart Association class II or III...
متن کامل[Interest of NT-proBNP in chronic heart failure follow-up].
Reducing readmissions after hospitalisation for acute heart failure is the new challenge of these diseases, approaching 30% within 60 to 90 days of discharge. Congestion related to high ventricular filling pressures, reflected by the high levels of natriuretic peptides, is the main reason for heart failure readmission. Natriuretic peptide levels are a patent prognostic marker of cardiovascular ...
متن کاملNT-proBNP for heart failure diagnosis in primary care
The accurate diagnosis of heart failure (HF) presenting in primary care is difficult. Clinical assessment of symptoms and signs has limited sensitivity and specificity. Patients are often elderly with comorbidity, symptoms may be mild, and echocardiography may not be universally available [1, 2, 3]. Overdiagnosis of HF in the community is a well-documented phenomenon, with only a quarter to a t...
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ژورنال
عنوان ژورنال: Cardiovascular Diabetology
سال: 2013
ISSN: 1475-2840
DOI: 10.1186/1475-2840-12-72